Is there a gene which causes Bipolar Disorder? Yes. And no.
“The genetic basis of Bipolar Disorder probably involves multiple genes interacting with each other and with external stimuli in ways which we have not figured out yet. Bipolar disorder frequently occurs within families, although genetic factors account for only about 60% of cases” (source)
Bipolar disorder is seen as a gift and a curse among people who suffer with it. Although many incredibly creative people claim they have been helped by the manic phase, the inevitable depressive phase can be so bad that many need to exert a great deal of extra energy in order to lead as normal a life as possible. Proper medical care can help many who suffer with Bipolar disorder. The best combination would be a person doing their work as well as being under thoughtful and educated care for their disease.
Bipolar depression is defined by cyclical disturbances in mood, thoughts, and behavior. Bipolar disorder affects both sexes equally. It seems to affect about 1% of the general population. It seems to be that if one parent is diagnosed with Bipolar a child may have about a 25% chance of also having Bipolar. If both parents have Bipolar disorder the percentage could be as high as 65% for a child of those parents.
Bipolar disorder runs in families. More than two-thirds of those diagnosed with bipolar disorder have at least one close relative with bipolar disorder or clinical depression.
Research has failed to pinpoint a single gene or chromosome as the precise cause of Bipolar disorder. Ken Kendlar (psychiatrist at the Medical College of VA in Richmond) believes that it is a 50 – 50 split between genetics and environment when it comes to developing a mental disorder. (source) Other sources report that the ratio is more of an 80 (genetic) – 20 (environmental) split.
While we wait for science to attribute the genetic piece of Bipolar disorder, what
are some of the environmental factors that may play into the mix?
Environmental influences can be obvious such as:
- family relations,
- abuse (physical & mental),
- physical illnesses,
- possible head trauma in childhood or other medical events,
- stress and traumatic experiences.
The influences may also be self-imposed, including:
- the abuse of drugs, both illegal, prescription, and over the counter,
- a poor diet– which affects brain and body chemistry in a negative way.
- There are other possible contributors, which include allergens, exposure to toxic chemicals, heavy metals, noise, carbon monoxide and non-specified pollution. (source)
The brain at risk for bipolar disorder may experience certain events as stressful that a brain
without bipolar genes might perceive as minor. So it could be that it doesn’t take a really big stress to turn on the gene. It depends on the genes and the severity of the vulnerability–the degree of predisposition a particular individual may have to Bipolar disorder.
Remember: Even if you do everything “right,” you can’t control everything in anyone else’s life let alone your own, and even if you could, there’s no guarantee that it would prevent the onset of bipolar disorder. It is crucial to avoid the “blame game” at all costs. Establishing an atmosphere of mutual respect and kindness is most important.
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